The dosage of clonazepam must be adjusted to the needs of each individual and depends on the individual response to therapy.
No adverse maternal or embryo-fetal effects were observed in either mice or rats following administration of oral clonazepam during organogenesis, at doses of up to 20 or 40 mg/kg/day, respectively. In several rabbit studies following doses of clonazepam of up to 20 mg/kg/day, a low, non-dose-related incidence of a similar pattern of malformations (cleft palate, open eyelids, fused sternebrae and limb defects) was observed (see section 4.6 Pregnancy and Lactation). 6. Pharmaceutical particulars 6.1 List of excipients Saccharin Ethanol Levomenthol Medium chain triglycerides 6.2 Incompatibilities In the absence of compatibility studies this medicinal product must not be mixed with other medicinal products.
NDC Code(s): , , ; Packager: Unit Dose Services; This is a repackaged label. Source NDC Code(s):.
Controlled studies examining the influence of gender and age on clonazepam pharmacokinetics have not been conducted, nor have the effects of renal or liver disease on clonazepam pharmacokinetics been studied. Because clonazepam undergoes hepatic metabolism, it is possible that liver disease will impair clonazepam elimination. Thus, caution should be exercised when administering clonazepam to these patients.
Clonazepam is rapidly and compley absorbed after oral administration. The absolute bioavailability of clonazepam is about 90%.
The objective of this paper was to determine how long after administration of benzodiazepine clonazepam (CLO), its major metabolite 7-aminoclonazepam.
Abstract The objective of this paper was to determine how long after administration of benzodiazepine clonazepam (CLO), its major metabolite 7-aminoclonazepam (7-ACLO) could be detected in urine collected from 10 healthy vol- unteers who received a single 3-mg dose of Klonopin (clonazepam). Such data would be of great importance to law enforcement agencies trying to determine the best time in- terval for urine collection from a victim of drug-facilitated sexual assault in order to reveal drug use.
Do not double up on doses if you miss using your clonazepam (Klonopin) at the prescribed time. Use it as soon as you remember it unless you are close to your.
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People also get told that a dose of .5 milligrams of a drug like Clonazepam (Klonopin) is a low dose. A person will say confidently that s/he is.